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PRESS RELEASES |
2006 |
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| July |
TransForm
named as one of 2006 Best Places to Work by the Boston Business
Journal |
| April |
TransForm
Pharmaceuticals Ranks Second in The Scientist Magazine's "Best
Places to Work in Industry" Survey |
| 2005 |
|
June |
TransForm
Pharmaceuticals Named as one of the"Best Places To Work In Industry"
by The Scientist Magazine (PDF) |
April |
Johnson
& Johnson Completes Acquisition of TransForm Pharmaceuticals,
Inc.(PDF) |
March |
Johnson
& Johnson to Acquire TransForm Pharmaceuticals (PDF) |
PUBLICATIONS |
2007
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“Benzidine:
A Co-Crystallization Agent for Proton Acceptors.” Michal Rafilovich,
Joel Bernstein,* Magali B. Hickey, and Michael Tauber Crystal
Growth & Design 7 (9), 1777 -1782, 2007 |
| Oct. |
“Combined
Use of Crystalline Salt Forms and Precipitation Inhibitors to Improve
Oral Absorption of Celecoxib from Solid Oral Formulations.” Hector
Guzman, Mark Tawa, Zhong Zhang, Pasut Ratanabanangkoon, Paul Shaw,
Colin Gardner, Hongming Chen, Jean-Pierre Moreau, Orn Almarsson,
Jules Remenar Journal of Pharmaceutical Science Vol. 96, No. 10,
October 2007 |
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"Performance
comparison of a co-crystal of carbamazepine with marketed products." Magali
B. Hickey, Matthew L. Petterson, Lisa A. Scoppettuolo, Sherry L.
Morisette, Anna Vetter, Hecotr Guzman, Julius F. Remenar, Zhong
Zhang, Mark D. Tawa, Sean Haley, Michael J. Zaworotko, Orn Almarsson European
Journal of Pharmaceutics and Biopharmaceutics 67 (2007) 112-119 |
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“Making
Co-Crystals-The Utility of Ternary Phase Diagrams.” Renato
A. Chiarella, Roger J. Davey, and Matthew L. Peterson. Crystal
Growth & Design; 2007; 7(7) pp 1223 - 1226 |
May
|
“Hydrates
and Solid-State Reactivity: A Survey of B-Lactam Antibiotics.” Magali
B. Hickey, Matthew L. Peterson, Eric S. Manas, Juan Alvarez, Fredrik
Haeffner, Orn Almarsson Journal of Pharmaceutical Sciences Vol.
96, No. 5, May 2007
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January
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"Combination
of automated high throughput platforms, flow cytometry, and hierarchical
clustering to detect cell state." Kitsos
CM, Bhamidipati P, Melnikova I, Cash EP, McNulty C, Furman J, Cima
MJ, Levinson D
Cytometry A. 2007 Jan 8; 71A(1): 16-27
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2006 |
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Sep.
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"Expanding
the Scope of Crystal form Evaluation in Pharmaceutical Science." Peterson, Matthew L.; Hickey, Magali B.; Zaworotko, Michael J.; Almarsson,
Orn. Journal
of Pharmacy & Pharmaceutical Sciences (2006),
9(3), 317-326. CODEN: JPPSFY ISSN:1482-1826. CAN 146:128172 AN 2006:1316420
CAPLUS |
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“17
Salts of Ephedrine: Crystal Structures and Packing Analysis.” E.
A. Collier, R. J. Davey, S. N. Black and R. J. Roberts. Structural
Science Acta Cryst. (2006). B62, 498-505 |
May
|
“Rational
Design of a Reversible pH-Responsive Switch for Peptide Self-Assembly.” Yuri
Zimenkov, Steven N. Dublin, Rong Ni, Raymond S. Tu, Victor Breedveld,
Robert P. Apkarian, and Vincent P. Conticello. Journal of the American
Chemical Society May 31, 2006 Volume 128, No. 21 |
March
|
“Design
of an i.v. Formulation of an Unstable Prodrug Candidate for Prostate
Cancer Treatment: Solution Chemistry of N-(glutaryl-hyp-ala-ser-cyclohexylglycyl-gln-ser-leu)-Doxorubicin.” Karki
SB, Treemaneekarn V, Ostovic D, Nerurkar M, Almarsson O. Drug Dev
Ind Pharm. 2006 Mar;32(3):327-34. |
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“The
Prevalence of Germline BRCA1 and BRCA2 Mutations in Young Women with
Breast Cancer Undergoing Breast-Conservation Therapy.” Mehra
Golsha, M.D., Alex Miron, Ph.D., Asa J. Nixon, M.D., Judy E. Garber,
M.D., Ethan P. Cash, B.A., James Dirk Iglehart, M.D., Jay R. Harris,
M.D., Julia S. Wong, M.D. The American Journal of Surgery, 192
(2006) 58-62 |
2005
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“Crystal
and Molecular Structure of Crotonohydroxamic Acid, and a Preliminary
Investigation of the Solid-State Reactivity of the Acid and its Salts”. Hickey, Magali B.; Foxman, Bruce M. Molecular Crystals and Liquid
Crystals (2005), 440 195-205. |
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“Crystal
Engineering of Pharmaceutical Co-Crystals from Polymorphic Active
Pharmaceutical Ingredients.” Vishweshwar, Peddy; McMahon, Jennifer
A.; Peterson, Matthew L.; Hickey, Magali B.; Shattock, Tanise R.;
Zaworotko, Michael J. Chemical Communications (Cambridge, United
Kingdom) (2005), (36), 4601-4603. |
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“Conformational
Polymorphism of Methacrylamide.” Guo, Chengyun; Hickey, Magali
B.; Guggenheim, Evan R.; Enkelmann, Volker; Foxman, Bruce M. Chemical
Communications (Cambridge, United Kingdom) (2005), (17), 2220-2222. |
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“The
Predictably Elusive Form II of Aspirin.” Vishweshwar,
Peddy; McMahon, Jennifer A.; Oliveira, Mark; Peterson, Matthew L.;
Zaworotko,
Michael J. Journal of the American Chemical Society (2005),
127(48), 16802-16803. |
Sep. |
“Nuclear
Imaging in the Pharmaceutical Industry: The Cost-Value-Benefit-Risk
Equation.” William E. Pullman, MD, PhD and P. David
Mozley. American Pharmaceutical Review, September/October 2005. |
Sep. |
“Calmodulin-dependent
Protein Kinase IV Regulates Hematopoietic Stem Cell Maintenance.”
Kitsos, Christine, Sankar U, Illario M, Colomer-Font JM, Duncan AW,
Ribar TJ, Reya T, Means AR, Journal of Biological Chemistry,
September 30, 2005 Volume 280, issue 39 pp33101-33108 |
|
“Virtual
Screening in Drug Discovery.” Edited by Juan Alvarez,
PhD and Brian Shoichet |
Mar. |
"A
Novel, Lipid-Free Nanodispersion Formulations of Propofol and Its
Characterization" Hongming Chen, Zhong Zhang, Örn
Almarsson, Jean-Francois Marier, Dina Berkovitz and Colin Gardner.
Pharmaceutical Research. Vol 22, No. 3, March 2005 |
2004 |
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Nov.
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"Drugs
as Materials: Valuing Physical Form in Drug Discovery.",
Colin R. Gardner, Christopher T. Walsh and Örn Almarsson, Nature
Reviews Drug Discovery, Vol 3 No 11. Pages 926-934. November,
2004. |
Sept.
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"Crystal
Engineering of the Composition of Pharmaceutical Phases. Do Pharmaceutical
Co-Crystals Represent a New Path to Improved Medicines?",*
Örn Almarsson and Michael J. Zaworotko, Chemical
Communications, Issue 17, September 7, 2004.
*Amongst the top ten articles accessed on the web from
the online version of Chemical Communications. |
August |
"Integration
of an Opto-mechanical Mass Sensor with a Powder-dispensing Device
for Microgram Sensitivity",
Jeanie Cherng, Javier Gonzalez-Zugasti, Nathan R. Kane, Michael
J. Cima, Anthony V. Lemmo, Journal of the Association of Laboratory
Automation (JALA), Vol. 9, Issue 4. Pages 228-237. August 2004
|
August |
"A
System for Dispensing Sub-Milligram Doses of Active Pharmaceutical
Powders for Early Stage Solubility Assays",
Nathan R. Kane, Brad Broce, Javier Gonzalez-Zugasti, Wendy
Pryce Lewis, Martin LeQuesne, Anthony V. Lemmo, Journal of the
Association of Laboratory Automation (JALA),Vol. 9, Issue 4. Pages
218-227. August 2004 |
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