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PRESS RELEASES

2006
 
July TransForm named as one of 2006 Best Places to Work by the Boston Business Journal
April TransForm Pharmaceuticals Ranks Second in The Scientist Magazine's "Best Places to Work in Industry" Survey
2005  

June

TransForm Pharmaceuticals Named as one of the"Best Places To Work In Industry" by The Scientist Magazine (PDF)

April

Johnson & Johnson Completes Acquisition of TransForm Pharmaceuticals, Inc.(PDF)

March

Johnson & Johnson to Acquire TransForm Pharmaceuticals (PDF)

PUBLICATIONS

2007
 
  “Benzidine: A Co-Crystallization Agent for Proton Acceptors.” Michal Rafilovich, Joel Bernstein,* Magali B. Hickey, and Michael Tauber Crystal Growth & Design 7 (9), 1777 -1782, 2007
Oct. “Combined Use of Crystalline Salt Forms and Precipitation Inhibitors to Improve Oral Absorption of Celecoxib from Solid Oral Formulations.” Hector Guzman, Mark Tawa, Zhong Zhang, Pasut Ratanabanangkoon, Paul Shaw, Colin Gardner, Hongming Chen, Jean-Pierre Moreau, Orn Almarsson, Jules Remenar Journal of Pharmaceutical Science Vol. 96, No. 10, October 2007
  "Performance comparison of a co-crystal of carbamazepine with marketed products." Magali B. Hickey, Matthew L. Petterson, Lisa A. Scoppettuolo, Sherry L. Morisette, Anna Vetter, Hecotr Guzman, Julius F. Remenar, Zhong Zhang, Mark D. Tawa, Sean Haley, Michael J. Zaworotko, Orn Almarsson European Journal of Pharmaceutics and Biopharmaceutics 67 (2007) 112-119
  “Making Co-Crystals-The Utility of Ternary Phase Diagrams.” Renato A. Chiarella, Roger J. Davey, and Matthew L. Peterson. Crystal Growth & Design; 2007; 7(7) pp 1223 - 1226
May

“Hydrates and Solid-State Reactivity: A Survey of B-Lactam Antibiotics.” Magali B. Hickey, Matthew L. Peterson, Eric S. Manas, Juan Alvarez, Fredrik Haeffner, Orn Almarsson Journal of Pharmaceutical Sciences Vol. 96, No. 5, May 2007

January

"Combination of automated high throughput platforms, flow cytometry, and hierarchical clustering to detect cell state." Kitsos CM, Bhamidipati P, Melnikova I, Cash EP, McNulty C, Furman J, Cima MJ, Levinson D Cytometry A. 2007 Jan 8; 71A(1): 16-27

2006
 
   
Sep.
"Expanding the Scope of Crystal form Evaluation in Pharmaceutical Science." Peterson, Matthew L.; Hickey, Magali B.; Zaworotko, Michael J.; Almarsson, Orn. Journal of Pharmacy & Pharmaceutical Sciences (2006), 9(3), 317-326. CODEN: JPPSFY ISSN:1482-1826. CAN 146:128172 AN 2006:1316420 CAPLUS
“17 Salts of Ephedrine: Crystal Structures and Packing Analysis.” E. A. Collier, R. J. Davey, S. N. Black and R. J. Roberts. Structural Science Acta Cryst. (2006). B62, 498-505
May
“Rational Design of a Reversible pH-Responsive Switch for Peptide Self-Assembly.” Yuri Zimenkov, Steven N. Dublin, Rong Ni, Raymond S. Tu, Victor Breedveld, Robert P. Apkarian, and Vincent P. Conticello. Journal of the American Chemical Society May 31, 2006 Volume 128, No. 21
March
“Design of an i.v. Formulation of an Unstable Prodrug Candidate for Prostate Cancer Treatment: Solution Chemistry of N-(glutaryl-hyp-ala-ser-cyclohexylglycyl-gln-ser-leu)-Doxorubicin.” Karki SB, Treemaneekarn V, Ostovic D, Nerurkar M, Almarsson O. Drug Dev Ind Pharm. 2006 Mar;32(3):327-34.
“The Prevalence of Germline BRCA1 and BRCA2 Mutations in Young Women with Breast Cancer Undergoing Breast-Conservation Therapy.” Mehra Golsha, M.D., Alex Miron, Ph.D., Asa J. Nixon, M.D., Judy E. Garber, M.D., Ethan P. Cash, B.A., James Dirk Iglehart, M.D., Jay R. Harris, M.D., Julia S. Wong, M.D. The American Journal of Surgery, 192 (2006) 58-62
2005
 
“Crystal and Molecular Structure of Crotonohydroxamic Acid, and a Preliminary Investigation of the Solid-State Reactivity of the Acid and its Salts”. Hickey, Magali B.; Foxman, Bruce M. Molecular Crystals and Liquid Crystals (2005), 440 195-205.
“Crystal Engineering of Pharmaceutical Co-Crystals from Polymorphic Active Pharmaceutical Ingredients.” Vishweshwar, Peddy; McMahon, Jennifer A.; Peterson, Matthew L.; Hickey, Magali B.; Shattock, Tanise R.; Zaworotko, Michael J. Chemical Communications (Cambridge, United Kingdom) (2005), (36), 4601-4603.
“Conformational Polymorphism of Methacrylamide.” Guo, Chengyun; Hickey, Magali B.; Guggenheim, Evan R.; Enkelmann, Volker; Foxman, Bruce M. Chemical Communications (Cambridge, United Kingdom) (2005), (17), 2220-2222.
“The Predictably Elusive Form II of Aspirin.” Vishweshwar, Peddy; McMahon, Jennifer A.; Oliveira, Mark; Peterson, Matthew L.; Zaworotko, Michael J. Journal of the American Chemical Society (2005), 127(48), 16802-16803.
Sep.
“Nuclear Imaging in the Pharmaceutical Industry: The Cost-Value-Benefit-Risk Equation.” William E. Pullman, MD, PhD and P. David Mozley. American Pharmaceutical Review, September/October 2005.
Sep.
“Calmodulin-dependent Protein Kinase IV Regulates Hematopoietic Stem Cell Maintenance.” Kitsos, Christine, Sankar U, Illario M, Colomer-Font JM, Duncan AW, Ribar TJ, Reya T, Means AR, Journal of Biological Chemistry, September 30, 2005 Volume 280, issue 39 pp33101-33108
“Virtual Screening in Drug Discovery.” Edited by Juan Alvarez, PhD and Brian Shoichet
Mar.
"A Novel, Lipid-Free Nanodispersion Formulations of Propofol and Its Characterization" Hongming Chen, Zhong Zhang, Örn Almarsson, Jean-Francois Marier, Dina Berkovitz and Colin Gardner. Pharmaceutical Research. Vol 22, No. 3, March 2005
2004
 
Nov.
"Drugs as Materials: Valuing Physical Form in Drug Discovery.", Colin R. Gardner, Christopher T. Walsh and Örn Almarsson, Nature Reviews Drug Discovery, Vol 3 No 11. Pages 926-934. November, 2004.
Sept.

"Crystal Engineering of the Composition of Pharmaceutical Phases. Do Pharmaceutical Co-Crystals Represent a New Path to Improved Medicines?",*
Örn Almarsson and Michael J. Zaworotko, Chemical Communications, Issue 17, September 7, 2004.

*Amongst the top ten articles accessed on the web from the online version of Chemical Communications.

August
"Integration of an Opto-mechanical Mass Sensor with a Powder-dispensing Device for Microgram Sensitivity",
Jeanie Cherng, Javier Gonzalez-Zugasti, Nathan R. Kane, Michael J. Cima, Anthony V. Lemmo, Journal of the Association of Laboratory Automation (JALA), Vol. 9, Issue 4. Pages 228-237. August 2004
August
"A System for Dispensing Sub-Milligram Doses of Active Pharmaceutical Powders for Early Stage Solubility Assays",
Nathan R. Kane, Brad Broce, Javier Gonzalez-Zugasti, Wendy Pryce Lewis, Martin LeQuesne, Anthony V. Lemmo, Journal of the Association of Laboratory Automation (JALA),Vol. 9, Issue 4. Pages 218-227. August 2004
   

 

 








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